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CD4(+) T cells recognize diverse epitopes within GAD65: implications for repertoire development and diabetes monitoring

Type 1 diabetes is associated with T‐cell responses to β‐cell antigens such as GAD65. Single T‐cell epitopes have been investigated for immune monitoring with some success, but multiple epitopes may be required to fully characterize responses in all subjects. We used a systematic approach to examine...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yang, Junbao, James, Eddie A., Sanda, Srinath, Greenbaum, Carla, Kwok, William W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573280/
https://ncbi.nlm.nih.gov/pubmed/23228173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12034
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