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CD4(+) T cells recognize diverse epitopes within GAD65: implications for repertoire development and diabetes monitoring

Type 1 diabetes is associated with T‐cell responses to β‐cell antigens such as GAD65. Single T‐cell epitopes have been investigated for immune monitoring with some success, but multiple epitopes may be required to fully characterize responses in all subjects. We used a systematic approach to examine...

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Detalhes bibliográficos
Main Authors: Yang, Junbao, James, Eddie A., Sanda, Srinath, Greenbaum, Carla, Kwok, William W.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573280/
https://ncbi.nlm.nih.gov/pubmed/23228173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12034
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