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p38 MAPK alpha mediates cytokine-induced IL-6 and MMP-3 expression in human cardiac fibroblasts

Pre-clinical studies suggest that the p38 MAPK signaling pathway plays a detrimental role in cardiac remodeling, but its role in cardiac fibroblast (CF) function is not well defined. We aimed to identify the p38 MAPK subtypes expressed by human CF, study their activation in response to proinflammato...

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Detalhes bibliográficos
Main Authors: Sinfield, John K., Das, Anupam, O’Regan, David J., Ball, Stephen G., Porter, Karen E., Turner, Neil A.
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573232/
https://ncbi.nlm.nih.gov/pubmed/23206705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.11.071
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