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Loss of SOX10 function contributes to the phenotype of human Merlin-null schwannoma cells

Loss of the Merlin tumour suppressor causes abnormal de-differentiation and proliferation of Schwann cells and formation of schwannoma tumours in patients with neurofibromatosis type 2. Within the mature peripheral nerve the normal development, differentiation and maintenance of myelinating and non-...

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Detalhes bibliográficos
Main Authors: Doddrell, Robin D. S., Dun, Xin-Peng, Shivane, Aditya, Feltri, M. Laura, Wrabetz, Lawrence, Wegner, Michael, Sock, Elisabeth, Hanemann, C. Oliver, Parkinson, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572932/
https://ncbi.nlm.nih.gov/pubmed/23413263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aws353
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