Global Proteome and Phospho-proteome Analysis of Merlin-deficient Meningioma and Schwannoma Identifies PDLIM2 as a Novel Therapeutic Target

Loss or mutation of the tumour suppressor Merlin predisposes individuals to develop multiple nervous system tumours, including schwannomas and meningiomas, sporadically or as part of the autosomal dominant inherited condition Neurofibromatosis 2 (NF2). These tumours display largely low grade feature...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Bassiri, Kayleigh, Ferluga, Sara, Sharma, Vikram, Syed, Nelofer, Adams, Claire L., Lasonder, Edwin, Hanemann, C Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474504/
https://ncbi.nlm.nih.gov/pubmed/28126595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.01.020
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