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Type I interferons: diversity of sources, production pathways and effects on immune responses

Type I interferons (IFN-I) were first described over 50 years ago as factors produced by cells that interfere with virus replication and promote an antiviral state. Innate and adaptive immune responses to viruses are also greatly influenced by IFN-I. In this article we discuss the diversity of cellu...

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Bibliographic Details
Main Authors: Swiecki, Melissa, Colonna, Marco
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572907/
https://ncbi.nlm.nih.gov/pubmed/22440910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2011.10.026
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