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A diverse array of gene products are effectors of the type I interferon antiviral response

The type I interferon (IFN) response protects cells from invading viral pathogens. The cellular factors that mediate this defense are the products of interferon-stimulated genes (ISGs). Although hundreds of ISGs have been identified since their discovery over 25 years ago(1,2,3), only few have been...

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Autors principals: Schoggins, John W., Wilson, Sam J., Panis, Maryline, Murphy, Mary Y., Jones, Christopher T., Bieniasz, Paul, Rice, Charles M.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409588/
https://ncbi.nlm.nih.gov/pubmed/21478870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09907
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