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Seeing Citrulline: Development of a phenylglyoxal-based probe to visualize protein citrullination

The Protein Arginine Deiminases (PADs) catalyze the hydrolysis of peptidyl-arginine to form peptidylcitrulline. Abnormally high PAD activity is observed in a host of human diseases, however, the exact role of protein citrullination in these diseases, as well as the identities of specific citrullinat...

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Detalhes bibliográficos
Main Authors: Bicker, Kevin L., Subramanian, Venkataraman, Chumanevich, Alexander A., Hofseth, Lorne J., Thompson, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572846/
https://ncbi.nlm.nih.gov/pubmed/23030787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja308871v
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