Epidermal growth factor receptors destined for the nucleus are internalized via a clathrin-dependent pathway

The epidermal growth factor (EGF) transduces its actions via the EGF receptor (EGFR), which can traffic from the plasma membrane to either the cytoplasm or the nucleus. However, the mechanism by which EGFR reaches the nucleus is unclear. To investigate these questions, liver cells were analyzed by i...

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Main Authors: De Angelis Campos, Ana Carolina, Rodrigues, Michele Angela, de Andrade, Carolina, de Goes, Alfredo Miranda, Nathanson, Michael H., Gomes, Dawidson A.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572844/
https://ncbi.nlm.nih.gov/pubmed/21821003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.07.100
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