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Role for Dpy-30 in ES Cell-Fate Specification by Regulation of H3K4 Methylation within Bivalent Domains

Histone H3K4 methylation is associated with active genes and, along with H3K27 methylation, is part of a bivalent chromatin mark that typifies poised developmental genes in embryonic stem cells (ESCs). However, its functional roles in ESC maintenance and differentiation are not established. Here we...

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Detalhes bibliográficos
Main Authors: Jiang, Hao, Shukla, Abhijit, Wang, Xiaoling, Chen, Wei-yi, Bernstein, Bradley E., Roeder, Robert G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572774/
https://ncbi.nlm.nih.gov/pubmed/21335234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.01.020
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