Notch Receptors and Smad3 Signaling Cooperate in the Induction of Interleukin-9-Producing T Cells
Interleukin 9 (IL-9) is a pleiotropic cytokine that can regulate autoimmune responses by enhancing regulatory CD4(+)FoxP3(+) T regulatory (Treg) cell survival and T helper 17 (Th17) cell proliferation. Here, we analyzed the costimulatory requirements for the induction of Th9 cells, and demonstrated...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3572366/ https://ncbi.nlm.nih.gov/pubmed/22503540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.01.020 |
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