Notch Receptors and Smad3 Signaling Cooperate in the Induction of Interleukin-9-Producing T Cells

Interleukin 9 (IL-9) is a pleiotropic cytokine that can regulate autoimmune responses by enhancing regulatory CD4(+)FoxP3(+) T regulatory (Treg) cell survival and T helper 17 (Th17) cell proliferation. Here, we analyzed the costimulatory requirements for the induction of Th9 cells, and demonstrated...

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Main Authors: Elyaman, Wassim, Bassil, Ribal, Bradshaw, Elizabeth M., Orent, William, Lahoud, Youmna, Zhu, Bing, Radtke, Freddy, Yagita, Hideo, Khoury, Samia J.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572366/
https://ncbi.nlm.nih.gov/pubmed/22503540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.01.020
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