Transcription elongation factor Tcea3 regulates the pluripotent differentiation potential of mouse embryonic stem cells, via the Lefty1-Nodal-Smad2 pathway

Self-renewal and pluripotency are hallmark properties of pluripotent stem cells, including embryonic stem cells (ESCs) and iPS cells. Previous studies revealed the ESC-specific core transcription circuitry and showed that these core factors (e.g., Oct3/4, Sox2, and Nanog) regulate not only self-rene...

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Main Authors: Park, Kyung-Soon, Cha, Young, Kim, Chun-Hyung, Ahn, Hee-Jin, Kim, Dohoon, Ko, Sanghyeok, Kim, Kyeoung-Hwa, Chang, Mi-Yoon, Ko, Jong-Hyun, Noh, Yoo-Sun, Han, Yong-Mahn, Kim, Jonghwan, Song, Jihwan, Kim, Jin Young, Tesar, Paul J., Lanza, Robert, Lee, Kyung-Ah, Kim, Kwang-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572291/
https://ncbi.nlm.nih.gov/pubmed/23169579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1284
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