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A “forward genomics” approach links genotype to phenotype using independent phenotypic losses among related species
Genotype-phenotype mapping is hampered by countless genomic changes between species. We introduce a computational “forward genomics” strategy that – given only an independently lost phenotype and whole genomes – matches genomic and phenotypic loss patterns to associate specific genomic regions with...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3572205/ https://ncbi.nlm.nih.gov/pubmed/23022484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.08.032 |
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