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Edgotype: the link between genotype and phenotype

Classical ‘one-gene/one-disease’ models cannot fully reconcile with the increasingly appreciated prevalence of complicated genotype-to-phenotype associations in human disease. Genes and gene products function not in isolation but as components of intricate networks of macromolecules (DNA, RNA, or pr...

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Détails bibliographiques
Auteurs principaux: Sahni, Nidhi, Yi, Song, Zhong, Quan, Jailkhani, Noor, Charloteaux, Benoit, Cusick, Michael E, Vidal, Marc
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902775/
https://ncbi.nlm.nih.gov/pubmed/24287335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2013.11.002
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