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Expression Profiles of SnoN in Normal and Cancerous Human Tissues Support Its Tumor Suppressor Role in Human Cancer

SnoN is a negative regulator of TGF-β signaling and also an activator of the tumor suppressor p53 in response to cellular stress. Its role in human cancer is complex and controversial with both pro-oncogenic and anti-oncogenic activities reported. To clarify its role in human cancer and provide clin...

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Detalhes bibliográficos
Main Authors: Jahchan, Nadine S., Ouyang, Gaoliang, Luo, Kunxin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572181/
https://ncbi.nlm.nih.gov/pubmed/23418461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055794
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