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De-Regulation of JNK and JAK/STAT Signaling in ESCRT-II Mutant Tissues Cooperatively Contributes to Neoplastic Tumorigenesis

Multiple genes involved in endocytosis and endosomal protein trafficking in Drosophila have been shown to function as neoplastic tumor suppressor genes (nTSGs), including Endosomal Sorting Complex Required for Transport-II (ESCRT-II) components vacuolar protein sorting 22 (vps22), vps25, and vps36....

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書誌詳細
主要な著者: Woodfield, Sarah E., Graves, Hillary K., Hernandez, Jacob A., Bergmann, Andreas
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572140/
https://ncbi.nlm.nih.gov/pubmed/23418496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056021
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