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De-Regulation of JNK and JAK/STAT Signaling in ESCRT-II Mutant Tissues Cooperatively Contributes to Neoplastic Tumorigenesis

Multiple genes involved in endocytosis and endosomal protein trafficking in Drosophila have been shown to function as neoplastic tumor suppressor genes (nTSGs), including Endosomal Sorting Complex Required for Transport-II (ESCRT-II) components vacuolar protein sorting 22 (vps22), vps25, and vps36....

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Detalhes bibliográficos
Main Authors: Woodfield, Sarah E., Graves, Hillary K., Hernandez, Jacob A., Bergmann, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572140/
https://ncbi.nlm.nih.gov/pubmed/23418496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056021
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