Caspase-8 Binding to Cardiolipin in Giant Unilamellar Vesicles Provides a Functional Docking Platform for Bid

Caspase-8 is involved in death receptor-mediated apoptosis in type II cells, the proapoptotic programme of which is triggered by truncated Bid. Indeed, caspase-8 and Bid are the known intermediates of this signalling pathway. Cardiolipin has been shown to provide an anchor and an essential activatin...

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Bibliographische Detailangaben
Hauptverfasser: Jalmar, Olivier, François-Moutal, Liberty, García-Sáez, Ana-Jesus, Perry, Mark, Granjon, Thierry, Gonzalvez, François, Gottlieb, Eyal, Ayala-Sanmartin, Jesus, Klösgen, Beate, Schwille, Petra, Petit, Patrice X.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572128/
https://ncbi.nlm.nih.gov/pubmed/23418437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055250
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