Accelerated Cell Aging in Female APOE-ε4 Carriers: Implications for Hormone Therapy Use

Apolipoprotein-ε4 (APOE-ε4) is a major genetic risk factor for cognitive decline, Alzheimer's disease (AD) and early mortality. An accelerated rate of biological aging could contribute to this increased risk. Here, we determined whether APOE-ε4 status impacts leukocyte telomere length (TL) and...

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Detalhes bibliográficos
Main Authors: Jacobs, Emily G., Kroenke, Candyce, Lin, Jue, Epel, Elissa S., Kenna, Heather A., Blackburn, Elizabeth H., Rasgon, Natalie L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572118/
https://ncbi.nlm.nih.gov/pubmed/23418430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054713
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