Connectome Signatures of Hyperexcitation in Cognitively Intact Middle-Aged Female APOE-ε4 Carriers

Synaptic dysfunction is hypothesized to be one of the earliest brain changes in Alzheimer’s disease, leading to “hyperexcitability” in neuronal circuits. In this study, we evaluated a novel hyperexcitation indicator (HI) for each brain region using a hybrid resting-state structural connectome to pro...

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Publicat a:Cereb Cortex
Autors principals: Fortel, Igor, Korthauer, Laura E, Morrissey, Zachery, Zhan, Liang, Ajilore, Olusola, Wolfson, Ouri, Driscoll, Ira, Schonfeld, Dan, Leow, Alex
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7609923/
https://ncbi.nlm.nih.gov/pubmed/32662517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhaa190
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