Mammalian TIMELESS Is Involved in Period Determination and DNA Damage-Dependent Phase Advancing of the Circadian Clock

The transcription/translation feedback loop-based molecular oscillator underlying the generation of circadian gene expression is preserved in almost all organisms. Interestingly, the animal circadian clock proteins CRYPTOCHROME (CRY), PERIOD (PER) and TIMELESS (TIM) are strongly conserved at the ami...

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Autors principals: Engelen, Erik, Janssens, Roel C., Yagita, Kazuhiro, Smits, Veronique A. J., van der Horst, Gijsbertus T. J., Tamanini, Filippo
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572085/
https://ncbi.nlm.nih.gov/pubmed/23418588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056623
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