Mammalian TIMELESS Is Involved in Period Determination and DNA Damage-Dependent Phase Advancing of the Circadian Clock

The transcription/translation feedback loop-based molecular oscillator underlying the generation of circadian gene expression is preserved in almost all organisms. Interestingly, the animal circadian clock proteins CRYPTOCHROME (CRY), PERIOD (PER) and TIMELESS (TIM) are strongly conserved at the ami...

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Detalhes bibliográficos
Main Authors: Engelen, Erik, Janssens, Roel C., Yagita, Kazuhiro, Smits, Veronique A. J., van der Horst, Gijsbertus T. J., Tamanini, Filippo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572085/
https://ncbi.nlm.nih.gov/pubmed/23418588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056623
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