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Proliferation-Linked Apoptosis of Adoptively Transferred T Cells after IL-15 Administration in Macaques

The adoptive transfer of antigen-specific effector T cells is being used to treat human infections and malignancy. T cell persistence is a prerequisite for therapeutic efficacy, but reliably establishing a high-level and durable T cell response by transferring cultured CD8(+) T cells remains challen...

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Autors principals: Berger, Carolina, Berger, Michael, Beard, Brian C., Kiem, Hans-Peter, Gooley, Theodore A., Riddell, Stanley R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572023/
https://ncbi.nlm.nih.gov/pubmed/23418547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056268
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