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Simple binary segmentation frameworks for identifying variation in DNA copy number

BACKGROUND: Variation in DNA copy number, due to gains and losses of chromosome segments, is common. A first step for analyzing DNA copy number data is to identify amplified or deleted regions in individuals. To locate such regions, we propose a circular binary segmentation procedure, which is based...

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Sonraí Bibleagrafaíochta
Príomhúdar: Yang, Tae Young
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571941/
https://ncbi.nlm.nih.gov/pubmed/23107320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-277
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