Bone Marrow Transplantation Confers Modest Benefits in Mouse Models of Huntington's Disease

Huntington's disease (HD) is caused by an expanded polyglutamine tract in the protein huntingtin (htt). Although HD has historically been viewed as a brain-specific disease, htt is expressed ubiquitously, and recent studies indicate that mutant htt might cause changes to the immune system that...

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Autores principales: Kwan, Wanda, Magnusson, Anna, Chou, Austin, Adame, Anthony, Carson, Monica J., Kohsaka, Shinichi, Masliah, Eliezer, Möller, Thomas, Ransohoff, Richard, Tabrizi, Sarah J., Björkqvist, Maria, Muchowski, Paul J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2012
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571858/
https://ncbi.nlm.nih.gov/pubmed/22219276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4846-11.2012
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