Bone Marrow Transplantation Confers Modest Benefits in Mouse Models of Huntington's Disease

Huntington's disease (HD) is caused by an expanded polyglutamine tract in the protein huntingtin (htt). Although HD has historically been viewed as a brain-specific disease, htt is expressed ubiquitously, and recent studies indicate that mutant htt might cause changes to the immune system that...

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Detalhes bibliográficos
Main Authors: Kwan, Wanda, Magnusson, Anna, Chou, Austin, Adame, Anthony, Carson, Monica J., Kohsaka, Shinichi, Masliah, Eliezer, Möller, Thomas, Ransohoff, Richard, Tabrizi, Sarah J., Björkqvist, Maria, Muchowski, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571858/
https://ncbi.nlm.nih.gov/pubmed/22219276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4846-11.2012
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