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Design Requirements for Interfering Particles To Maintain Coadaptive Stability with HIV-1

Defective interfering particles (DIPs) are viral deletion mutants lacking essential transacting or packaging elements and must be complemented by wild-type virus to propagate. DIPs transmit through human populations, replicating at the expense of the wild-type virus and acting as molecular parasites...

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Detalles Bibliográficos
Main Authors: Rouzine, Igor M., Weinberger, Leor S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571494/
https://ncbi.nlm.nih.gov/pubmed/23221552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02741-12
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