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An Evolutionary Role for HIV Latency in Enhancing Viral Transmission

HIV latency is the chief obstacle to eradicating HIV but is widely believed to be an evolutionary accident providing no lentiviral fitness advantage. However, findings of latency being “hardwired” into HIV’s gene-regulatory circuitry appear inconsistent with latency being an evolutionary accident, g...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Rouzine, Igor M., Weinberger, Ariel D., Weinberger, Leor S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488136/
https://ncbi.nlm.nih.gov/pubmed/25723173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.02.017
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