Tropism and Infectivity of Influenza Virus, Including Highly Pathogenic Avian H5N1 Virus, in Ferret Tracheal Differentiated Primary Epithelial Cell Cultures

Tropism and adaptation of influenza viruses to new hosts is partly dependent on the distribution of the sialic acid (SA) receptors to which the viral hemagglutinin (HA) binds. Ferrets have been established as a valuable in vivo model of influenza virus pathogenesis and transmission because of simila...

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Detalhes bibliográficos
Main Authors: Zeng, Hui, Goldsmith, Cynthia S., Maines, Taronna R., Belser, Jessica A., Gustin, Kortney M., Pekosz, Andrew, Zaki, Sherif R., Katz, Jacqueline M., Tumpey, Terrence M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571379/
https://ncbi.nlm.nih.gov/pubmed/23255802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02885-12
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