Tropism and Infectivity of Influenza Virus, Including Highly Pathogenic Avian H5N1 Virus, in Ferret Tracheal Differentiated Primary Epithelial Cell Cultures

Tropism and adaptation of influenza viruses to new hosts is partly dependent on the distribution of the sialic acid (SA) receptors to which the viral hemagglutinin (HA) binds. Ferrets have been established as a valuable in vivo model of influenza virus pathogenesis and transmission because of simila...

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Autors principals: Zeng, Hui, Goldsmith, Cynthia S., Maines, Taronna R., Belser, Jessica A., Gustin, Kortney M., Pekosz, Andrew, Zaki, Sherif R., Katz, Jacqueline M., Tumpey, Terrence M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571379/
https://ncbi.nlm.nih.gov/pubmed/23255802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02885-12
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