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Differential WNT activity in colorectal cancer confers limited tumorigenic potential and is regulated by MAPK signaling

Colorectal cancers (CRCs) express the WNT effector protein β-catenin in a heterogeneous subcellular pattern rather than uniformly in the nucleus. In this study, we investigated this important aspect of molecular heterogeneity in CRCs by analyzing its basis and relationship with tumor initiating capa...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Horst, David, Chen, Justina, Morikawa, Teppei, Ogino, Shuji, Kirchner, Thomas, Shivdasani, Ramesh A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571091/
https://ncbi.nlm.nih.gov/pubmed/22318865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3222
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