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An Adaptive, Dose-Finding, Seamless Phase 2/3 Study of a Long-Acting Glucagon-Like Peptide-1 Analog (Dulaglutide): Trial Design and Baseline Characteristics

Dulaglutide (dula, LY2189265) is a once-weekly glucagon-like peptide-1 analog in development for the treatment of type 2 diabetes mellitus. An adaptive, dose-finding, inferentially seamless phase 2/3 study was designed to support the development of this novel diabetes therapeutic. The study is divid...

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Autores principales: Geiger, Mary Jane, Skrivanek, Zachary, Gaydos, Brenda, Chien, Jenny, Berry, Scott, Berry, Donald, Anderson, James H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Diabetes Technology Society 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570871/
https://ncbi.nlm.nih.gov/pubmed/23294776
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