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Synthesis of Isoquinuclidines from Highly Substituted Dihydropyridines via the Diels-Alder Reaction

[Image: see text] A stereo- and regioselective Diels-Alder reaction for the synthesis of highly substituted isoquinuclidines from dihydropyridines and electron deficient alkenes has been developed. While reactions with activated dienophiles proceed readily under thermal conditions, the use of Lewis...

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Autori principali: Martin, Rhia M., Bergman, Robert G., Ellman, Jonathan A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570756/
https://ncbi.nlm.nih.gov/pubmed/23320852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol303040r
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