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Synthesis of Isoquinuclidines from Highly Substituted Dihydropyridines via the Diels-Alder Reaction

[Image: see text] A stereo- and regioselective Diels-Alder reaction for the synthesis of highly substituted isoquinuclidines from dihydropyridines and electron deficient alkenes has been developed. While reactions with activated dienophiles proceed readily under thermal conditions, the use of Lewis...

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Detalles Bibliográficos
Main Authors: Martin, Rhia M., Bergman, Robert G., Ellman, Jonathan A.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570756/
https://ncbi.nlm.nih.gov/pubmed/23320852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol303040r
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