Fingolimod reduces cerebral lymphocyte infiltration in experimental models of rodent intracerebral hemorrhage

T-lymphocytes promote cerebral inflammation, thus aggravating neuronal injury after stroke. Fingolimod, a sphingosine 1-phosphate receptor analog, prevents the egress of lymphocytes from primary and secondary lymphoid organs. Based on these findings, we hypothesized fingolimod treatment would reduce...

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Главные авторы: Rolland, William B., Lekic, Tim, Krafft, Paul R., Hasegawa, Yu, Altay, Orhan, Hartman, Richard, Ostrowski, Robert, Manaenko, Anatol, Tang, Jiping, Zhang, John H.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570752/
https://ncbi.nlm.nih.gov/pubmed/23261767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2012.12.009
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