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Fingolimod reduces cerebral lymphocyte infiltration in experimental models of rodent intracerebral hemorrhage
T-lymphocytes promote cerebral inflammation, thus aggravating neuronal injury after stroke. Fingolimod, a sphingosine 1-phosphate receptor analog, prevents the egress of lymphocytes from primary and secondary lymphoid organs. Based on these findings, we hypothesized fingolimod treatment would reduce...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3570752/ https://ncbi.nlm.nih.gov/pubmed/23261767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2012.12.009 |
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