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Abundant pyroglutamate-modified ABri and ADan peptides in extracellular and vascular amyloid deposits in familial British and Danish dementias

Familial British (FBD) and familial Danish dementia (FDD) are progressive neurodegenerative disorders characterized by cerebral deposition of the amyloidogenic peptides ABri and ADan. These amyloid peptides start with an N-terminal glutamate residue, which can be posttranslationally converted into a...

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Sonraí Bibleagrafaíochta
Main Authors: Saul, Anika, Lashley, Tammaryn, Revesz, Tamas, Holton, Janice, Ghiso, Jorge A., Coomaraswamy, Janaky, Wirths, Oliver
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570712/
https://ncbi.nlm.nih.gov/pubmed/23261769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2012.11.014
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