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Characterizing Polymorphisms and Allelic Diversity of von Willebrand Factor Gene in the 1000 Genomes
BACKGROUND: The von Willebrand factor (VWF) gene is highly polymorphic, with variants correlated with VWF antigen levels, adhesion activity, clearance, and factor VIII binding. VWF mutations are detected in patients with von Willebrand disease (VWD), whereas polymorphic variants could be associated...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3570679/ https://ncbi.nlm.nih.gov/pubmed/23216583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12093 |
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