DNA-dependent PK inhibits adeno-associated virus DNA integration

Recent studies have shown that recombinant adeno-associated virus (rAAV) can persist in episomal form; however, factors affecting rAAV persistence are poorly understood. DNA-dependent PK (DNA-PK) is a DNA repair enzyme, which we previously found played an important role in determining the molecular...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Song, Sihong, Lu, Yuanqing, Choi, Young-Kook, Han, Yinong, Tang, Qiushi, Zhao, Ge, Berns, Kenneth I., Flotte, Terence R.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2004
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC357060/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14766968/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307833100
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