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DNA-dependent PK inhibits adeno-associated virus DNA integration

Recent studies have shown that recombinant adeno-associated virus (rAAV) can persist in episomal form; however, factors affecting rAAV persistence are poorly understood. DNA-dependent PK (DNA-PK) is a DNA repair enzyme, which we previously found played an important role in determining the molecular...

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Detalhes bibliográficos
Main Authors: Song, Sihong, Lu, Yuanqing, Choi, Young-Kook, Han, Yinong, Tang, Qiushi, Zhao, Ge, Berns, Kenneth I., Flotte, Terence R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC357060/
https://ncbi.nlm.nih.gov/pubmed/14766968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307833100
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