Mitochondrial dysfunction in breast cancer cells prevents tumor growth: Understanding chemoprevention with metformin

Metformin is a well-established diabetes drug that prevents the onset of most types of human cancers in diabetic patients, especially by targeting cancer stem cells. Metformin exerts its protective effects by functioning as a weak “mitochondrial poison,” as it acts as a complex I inhibitor and preve...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sanchez-Alvarez, Rosa, Martinez-Outschoorn, Ubaldo E., Lamb, Rebecca, Hulit, James, Howell, Anthony, Gandara, Ricardo, Sartini, Marina, Rubin, Emanuel, Lisanti, Michael P., Sotgia, Federica
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570509/
https://ncbi.nlm.nih.gov/pubmed/23257779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23058
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados