Identification of CpG islands in DNA sequences using statistically optimal null filters

CpG dinucleotide clusters also referred to as CpG islands (CGIs) are usually located in the promoter regions of genes in a deoxyribonucleic acid (DNA) sequence. CGIs play a crucial role in gene expression and cell differentiation, as such, they are normally used as gene markers. The earlier CGI iden...

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Bibliographic Details
Main Authors: Kakumani, Rajasekhar, Ahmad, Omair, Devabhaktuni, Vijay
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570435/
https://ncbi.nlm.nih.gov/pubmed/22931396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1687-4153-2012-12
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