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B cell development and immunoglobulin transcription in Oct-1-deficient mice
The POU domain transcription factors Oct-1 and Oct-2 interact with the octamer element, a motif conserved within Ig promoters and enhancers, and mediate transcription from the Ig loci. Inactivation of Oct-2 by gene targeting results in normal B cell development and Ig transcription. To study the rol...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC357042/ https://ncbi.nlm.nih.gov/pubmed/14762167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307304101 |
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