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B cell development and immunoglobulin transcription in Oct-1-deficient mice

The POU domain transcription factors Oct-1 and Oct-2 interact with the octamer element, a motif conserved within Ig promoters and enhancers, and mediate transcription from the Ig loci. Inactivation of Oct-2 by gene targeting results in normal B cell development and Ig transcription. To study the rol...

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Detalhes bibliográficos
Main Authors: Wang, Victoria E. H., Tantin, Dean, Chen, Jianzhu, Sharp, Phillip A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC357042/
https://ncbi.nlm.nih.gov/pubmed/14762167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307304101
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