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Tracking the mechanical dynamics of human embryonic stem cell chromatin

BACKGROUND: A plastic chromatin structure has emerged as fundamental to the self-renewal and pluripotent capacity of embryonic stem (ES) cells. Direct measurement of chromatin dynamics in vivo is, however, challenging as high spatiotemporal resolution is required. Here, we present a new tracking-bas...

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Autors principals: Hinde, Elizabeth, Cardarelli, Francesco, Chen, Aaron, Khine, Michelle, Gratton, Enrico
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570407/
https://ncbi.nlm.nih.gov/pubmed/23259580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-5-20
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