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GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells
T helper type 2 (Th2) cells secrete IL-4, IL-5, IL-10, and IL-13 and mediate allergic and asthmatic disease. GATA-3 is a Th2-specific transcription factor that appears in overexpression studies and transgenic systems to function as a Th2 lineage determinant. Because GATA-3 is also crucial for develo...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
2004
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC357040/ https://ncbi.nlm.nih.gov/pubmed/14769923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308697100 |
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