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Cofilin peptide homologs interfere with immunological synapse formation and T cell activation

The formation of supramolecular activation clusters within the immunological synapse, crucial for sustained signaling and T lymphocyte activation, requires costimulation-dependent reorganization of the actin cytoskeleton. Here we have identified the actin-remodeling protein cofilin as a key player i...

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Detalhes bibliográficos
Main Authors: Eibert, Sybille M., Lee, Kyeong-Hee, Pipkorn, Rüdiger, Sester, Urban, Wabnitz, Guido H., Giese, Thomas, Meuer, Stefan C., Samstag, Yvonne
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC357034/
https://ncbi.nlm.nih.gov/pubmed/14762171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308282100
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