Association between urinary 6β-hydroxycortisol/cortisol ratio and CYP3A5 genotypes in a normotensive population

Genetic polymorphism of genes involved in renal salt handling and arterial vessel tone is considered to be one of the causes of hypertension. Numerous reports suggest that cytochrome P4503A5 (CYP3A5) catalyzes 6β-hydroxylation of endogenous cortisol (CS), which is associated with sodium and water re...

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Hlavní autoři: RAIS, NAUSHAD, HUSSAIN, ARIF, CHAWLA, YOGESH KUMAR, KOHLI, KRISHAN K.
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570147/
https://ncbi.nlm.nih.gov/pubmed/23404385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2012.842
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