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Erythropoietin-directed erythropoiesis depends on serpin inhibition of erythroblast lysosomal cathepsins
Erythropoietin (EPO) and its cell surface receptor (EPOR) are essential for red blood cell production and exert important cytoprotective effects on select vascular, immune, and cancer cells. To discover novel EPO action modes, we profiled the transcriptome of primary erythroid progenitors. We report...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3570101/ https://ncbi.nlm.nih.gov/pubmed/23319700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121762 |
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