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Protein homeostasis: live long, won’t prosper

Protein turnover is an effective way of maintaining a functional proteome, as old and potentially damaged polypeptides are destroyed and replaced by newly synthesized copies. An increasing number of intracellular proteins, however, have been identified that evade this turnover process and instead ar...

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Detalhes bibliográficos
Main Authors: Toyama, Brandon H., Hetzer, Martin W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570024/
https://ncbi.nlm.nih.gov/pubmed/23258296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3496
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